Can you tell me what I need to know about ketamine therapy?

ketamine therapy

Hello,

This is Dr Justin Yanuck MD and I’ve given myself 10 minutes to answer this patient question. This week’s question centers on the safety of ketamine

Question: “Can you tell me what I need to know about ketamine therapy?”

Answer:

Ketamine Therapy for Depression and Anxiety in Anaheim, CA: A Physician’s Perspective

By Dr. Justin Yanuck, MD
Medical Director, Renew Ketamine Infusion

If you’re reading this, you may be searching for ketamine therapy in Anaheim because traditional mental health treatments haven’t worked the way you hoped. Many of the patients I see every week arrive feeling discouraged, exhausted, and unsure what options remain. My goal here is to answer the most common questions people ask about ketamine, and to explain how we use it safely, thoughtfully, and effectively.

What Is Ketamine Therapy, Really?

Ketamine is not new. It has been used in hospitals for decades. What is relatively new is how we use ketamine at much lower doses to treat depression, anxiety, PTSD, and other mood disorders—especially when standard medications haven’t helped.

Unlike antidepressants that can take weeks to work, ketamine targets the brain’s glutamate system, which plays a key role in mood regulation and neuroplasticity. In simple terms, ketamine helps the brain form healthier connections more quickly.

At Renew Ketamine Infusion, located near Anaheim and serving patients across Orange County, ketamine is delivered intravenously in a medical setting, with continuous monitoring and individualized dosing.

What Conditions Can Ketamine Help Treat?

Most of the people we see come in for:

  • Treatment-resistant depression
  • Major depressive disorder
  • PTSD
  • Severe anxiety
  • Bipolar depression (depressive phase)
  • Persistent suicidal thoughts

If you’ve tried multiple medications, therapy, or even advanced treatments without lasting relief, ketamine may be worth considering.

How Fast Does Ketamine Work?

This is one of the most searched questions—and understandably so.

Some patients notice improvement within hours or days of their first infusion. Others experience a gradual lift over a short series of treatments. Compared to traditional antidepressants, ketamine works much faster, though it is not a one-time fix.

Most evidence-based protocols include an initial series of infusions followed by maintenance treatments as needed.

Is Ketamine Safe?

When administered in a medical clinic by trained professionals, ketamine is considered safe and well tolerated.

During every infusion, we monitor:

  • Blood pressure
  • Heart rate
  • Oxygen levels
  • Overall comfort and response

Short-term side effects can include dissociation, lightheadedness, or nausea, but these typically resolve within hours. Patients are never sedated or unconscious.

Is Ketamine Addictive?

This is another common concern.

Ketamine can be misused recreationally, but medical ketamine therapy is very different. Doses are controlled, treatments are spaced out, and everything happens under physician supervision. Research and clinical experience show that patients treated responsibly for depression do not develop addiction patterns.

We carefully screen every patient to ensure ketamine is appropriate.

What Does a Ketamine Infusion Feel Like?

Most patients describe feeling temporarily detached from their usual thought patterns. Many find that negative or intrusive thoughts lose their intensity.

People often report:

  • A sense of mental quiet
  • Emotional distance from distress
  • Increased clarity or perspective

These effects are temporary, but they often create an opening for meaningful psychological change.

How Long Do the Benefits Last?

This varies. Some patients experience relief lasting weeks or months. Others benefit from periodic maintenance infusions.

Ketamine works best when combined with ongoing mental health care. The goal is not just symptom relief but helping you reengage with your life during a window when your brain is more flexible and responsive.

Is Ketamine FDA-Approved for Depression?

Intravenous ketamine is used off-label, which is common in medicine and supported by substantial research. A related medication, esketamine (Spravato), is FDA-approved for treatment-resistant depression, further validating this approach.

Why Patients from Anaheim Choose Renew Ketamine Infusion

Patients come to us from Anaheim and throughout Orange County because we emphasize:

  • Physician-led care
  • Individualized treatment plans
  • Insurance Coverage
  • Medical oversight and safety
  • Collaboration with therapists and psychiatrists

Ketamine should never be offered as a shortcut or a promise. It requires careful evaluation, clear expectations, and ethical medical judgment.

Is Ketamine Right for You?

Ketamine isn’t for everyone. But if you feel stuck, hopeless, or worn down by years of ineffective treatment, it may offer a new direction.

The first step is a comprehensive consultation. Together, we determine whether ketamine makes sense for your specific situation.

You don’t have to keep doing this alone.

Ok, my 10 minutes is up. Hope that was helpful, as always, reach out anytime with questions, I’m happy to answer all questions regarding ketamine. You can reach me at info@renewketamineinfusion.com or book a free consultation at renewketamineinfusion.com

 

Cheers,

Dr. Justin Yanuck, MD

Renew Ketamine Infusion

Tustin, San Juan Capistrano, and Seal Beach

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OCD

Obsessive Compulsive disorder (OCD) is unfortunately resistant to many forms of medical treatment including both medication and therapy.

Ketamine has been shown to be an effective, fast acting, safe option for patients with OCD. Over the course of the Ketamine infusions (2-4 weeks) neuroplasticity can lead to a change or abatement in the intrusive, repetitive thoughts and behaviors that typify OCD.

When combined with our unique post infusion integration process, patients with severe OCD can see profound relief of their symptoms.

Start here for a free physician consultation to see if Ketamine assisted psychotherapy can help renew you.

Chronic Pain

“There is extensive research currently being done on this topic. I can say from personal experience as a practicing Board Certified Pain Medicine Physician, I have had patients with chronic pain, including fibromyalgia, who have had significant relief of their symptoms with Ketamine assisted therapy. With that said, Ketamine assisted therapy will definitely not work for everyone with chronic pain, and each patient will require a thorough evaluation to ensure they are an adequate candidate for a trial of Ketamine assisted therapy for relief of their chronic pain” -Dr. Justin Yanuck.

The current evidence of Ketamine assisted therapy for chronic pain is fairly mixed. The majority of studies only looked at ketamine infusion without any assisted psychotherapy.

Ketamine has the ability to lead to relief on its own (and the mechanisms for this have been well studied). We feel quite strongly that the real potential for Ketamine to provide relief, especially for chronic pain patients, is when combined with psychotherapy. Psychotherapy allows the individual to process their experience and build off this experience to lead to new psychological frameworks for processing both internal and external stimuli.

Pain is complex, and Ketamine assisted psychotherapy is not one-size-fits-all. Our treatment plan gives patients with treatment-resistant chronic pain and even opiate dependance a chance to try a different and effective treatment. Start here (button) for a free physician consultation to see if Ketamine assisted psychotherapy can help renew you.

Start here for a free physician consultation to see if Ketamine assisted psychotherapy can help renew you.

PTSD

Post Traumatic Stress Disorder (PTSD) is a major public health concern, affecting up to 7% of Americans.

As many as half of all Americans with PTSD get inadequate relief from traditional treatments which include antidepressants, antipsychotics, and cognitive behavioral therapy.

Ketamine combined with psychotherapy has been shown to be very effective at reducing the symptoms of PTSD. These effects last well beyond its near immediate relief.

Many mechanistic actions for how Ketamine works in PTSD have been proposed.

Ketamine allows people to reacquaint themselves with their past inciting trauma from an emotionally neutral perspective. Ketamine will not make you forget about the trauma. It can allow you to acknowledge its occurrence in a neutral way in order to not be continually re-traumatized by thinking about it.

Depending on the patient, outcomes can be noticed almost immediately with a sense of lightness and joy. Ketamine followed by psychotherapy has been shown to lead to significant relief of the burdens of PTSD.

Start here for a free physician consultation to see if Ketamine assisted psychotherapy can help renew you.

Anxiety

Traditional treatments for anxiety will often either work poorly, have addictive properties, or severe side effects including brain fog and drowsiness. Furthermore, these treatments tend to have reduced efficacy over time, and lead to only transient relief of symptoms.

Ketamine, when combined with our novel integrative psychotherapy, can lead to significant relief of anxiety.

During the ketamine infusion and integration process, patients will often get a better understanding of their anxiety, and are able to reframe many of the triggers that often provoke their anxiety.

Ketamine has properties that allow for rewiring of the brain (new synapse formation and repair of existing synapses). Ketamine allows people to effect changes into their own lives. It shows people that they have the power to heal from within and take control of their relationship with anxiety.

Start here for a free physician consultation to see if Ketamine assisted psychotherapy can help renew you.

Depression

Ketamine has been shown to be extremely effective and safe for patients with depression and treatment resistant depression (those who fail to get relief from two or more antidepressants).

Ketamine is highly effective at rapidly (within 2-8 hours) reducing depressive symptoms. Traditional antidepressants often take weeks to months to work.

Many traditional antidepressants have side effects including reduced libido, weight gain, GI upset, mood disturbances, and unfortunately require daily use for months to years.

Many antidepressants, even if they do work, require you to be on them for years, if not for the rest of your life.

Ketamine treatment has been shown in most patients to lead to resolution of symptoms without the need for any further medications.

Ketamine is not a medication meant to be taken for the rest of your life. The goal is to provide sustained relief after the completion of a set treatment plan. This is accomplished by combining the actions of Ketamine in the brain with psychotherapy. Additional enhancement sessions available as needed.

Unfortunately, there is a significant subset of patients that do not get significant relief from traditional cognitive behavioral therapy. Ketamine acts as a catalyst to stimulate a patient’s innate capacity for psychological healing. This allows patients to overcome past experiences and learned behavior to truly heal. Ketamine, combined with therapists who are specifically trained to work with psychedelic therapies, can lead to profound breakthroughs and deep psychological healing.

Start here for a free physician consultation to see if Ketamine assisted psychotherapy can help renew you.

Invite your friend/ relative/patient to try Ketamine infusion combined with integrative therapy

Invite them and renew their outlook

Ketamine infusion combined with integrative therapy to help you renew your outlook

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